DISCLAIMER: FOR RESEARCH USE ONLY. The material provided is "as is", and using TOPOGRAPH is without warranties of any kind, either expressed or implied. The content provided by this resource CANNOT subsitute for clinical judgement or professional oncology advice. Improper use of this resource may lead to harm.
NOTE: The haematology contents of this resource is currently under review and in the process of being updated.
Oncogenic mutation, Oncogenic mutations, Oncogenic mutations AND Loss of protein expression, Oncogenic mutations AND NOT Loss of protein expression, Loss-of-function mutations, Truncating mutations
Oncogenic mutation, Oncogenic mutations, Oncogenic mutations (germline), Loss of protein expression, Loss-of-function mutations, Loss-of-protein expression, Protein expression, Truncating mutations
BRAF:V600E AND KRAS:Oncogenic mutations, BRAF:V600E AND KRAS:A146, BRAF:V600E AND KRAS:G12, BRAF:V600E AND KRAS:G12D, BRAF:V600E AND KRAS:G13, BRAF:V600E AND KRAS:K117, BRAF:V600E AND KRAS:Q61, BRAF:V600E AND KRAS:Q61R
Amplification and Exon 19 deletion, C797S and Exon 19 deletion, E709K and Exon 19 deletion, G724S and Exon 19 deletion, G796S and Exon 19 deletion, L718 and Exon 19 deletion, L792H and Exon 19 deletion, Amplification and L858R, E709K and L858R, L718 and L858R, G724S and L858R, L792H and L858R, G796S and L858R, C797S and L858R, EGFR:T790M and EGFR:C797S and EGFR:T790M-C797S cis-allelic conformation
EGFR:Oncogenic mutation AND MET:amplification AND MET:D1228, EGFR:Oncogenic mutation AND MET:amplification AND MET:D1230, EGFR:Oncogenic mutations and MET:amplification, EGFR:Oncogenic mutations and MET:amplification and NOT EGFR:T790M, MET:Alteration and EGFR:Oncogenic mutations, MET:overexpression AND NOT EGFR:oncogenic mutation, EGFR:L858R and MET:exon 14 skipping mutation, EGFR:Exon 19 deletion and MET:amplification, EGFR:Exon 19 deletion and MET:exon 14 skipping mutation, MET:amplification and EGFR:exon 19 deletion, EGFR:L858R and MET:amplification, EGFR:T790M and MET:amplification, MET:amplification and EGFR:L858R
ERBB2:Oncogenic mutation and ERBB3:E928G, ERBB2:L755S and ERBB3:E928G, ERBB2:L869R and ERBB3:E928G, ERBB2:S310F and ERBB3:E928G, ERBB2:V777L and ERBB3:E928G
ERBB2:Amplification AND KRAS:Oncogenic mutations, ERBB2:Amplification and ERBB2:Protein expression and NOT KRAS:Oncogenic mutations and NOT BRAF:V600E, ERBB2:Oncogenic mutations AND KRAS:Oncogenic mutations, ERBB2:Overexpression AND KRAS:Oncogenic mutation, ERBB2:Overexpression AND KRAS:Oncogenic mutations, ERBB2:Overexpression and NOT KRAS:Oncogenic mutations and NOT BRAF:V600E, ERBB2:Protein expression AND KRAS:Oncogenic mutation, ERBB2:amplification and KRAS:G12, ERBB2:amplification and KRAS:G12D
ESR1:Protein expression and ESR1:oncogenic mutations and NOT ERBB2:amplification and NOT ERBB2:overexpression, ESR1:Protein expression and NOT ERBB2:amplification and NOT ERBB2:overexpression, NOT ESR1:protein expression and NOT ERBB2:amplified, NOT ESR1:protein expression and NOT ERBB2:overexpression
FGFR1-TACC3:fusion, FGFR1-TACC3:fusion_V1, FGFR1-TACC3:fusion_V3, FGFR3-BAIAP2L1 fusion, FGFR3-TACC3 fusion, Fusion, Fusions, High mRNA expression and FGFR3-TACC3 fusion, High mRNA expression and Oncogenic mutation, Oncogenic mutations, Oncogenic mutations and NOT V565 and NOT V550, Amplification, R248C, S249C, G370C, Y373C, Y375C, F386L, A393E, V443, N540K, V555G, V555K, V555L, V555M, L608V, K650E, K650M, Alteration, FGFR3 Y373C, High mRNA expression, High mRNA expression and G370C, High mRNA expression and R248C, High mRNA expression and S249C, High mRNA expression and Y373C, Overexpression
NOT KRAS:exon 2 mutation and NOT KRAS:exon 3 mutation and NOT KRAS:exon 4 mutation and NOT NRAS:exon 2 mutation and NOT NRAS:exon 3 mutation and NOT NRAS:exon 4 mutation
Oncogenic mutations, Oncogenic mutations (germline), Loss of promoter methylation, Loss-of-function mutations, Low protein expression, No protein expression, Promoter methylation
Oncogenic mutation, Oncogenic mutations, Heterozygous deletion, deletion, Copy number loss, Loss of protein expression, Loss-of-function mutation, Loss-of-function mutations